Blackburn defender Scott Dann faces a six-week absence after suffering a groin injury at the weekend.
Gael Givet will undergo minor surgery on a heart condition later this week but Junior Hoilett has recovered from a hamstring strain.
Bolton defender David Wheater is unavailable again as he serves the final match of his four-match ban.
Manager Owen Coyle has no new injury worries and will select from the same squad that lost at Fulham on Saturday.
MATCH PREVIEW
This Lancashire derby always has an edge. On Tuesday night the loser could topple over it.
Defeat would condemn either side to being bottom of the table at Christmas. That would appear to be particularly hazardous for Steve Kean, whose fate as Blackburn manager will reportedly be decided after this game.
Kean insists he has the backing of the club's owners, but this is a results-driven business and a return of 32 points from 37 games does not represent a successful first year in charge.
The hostility from Blackburn's fans is again likely to be directed at Kean, rather than Bolton - not that the visitors can take much satisfaction from that given their own failings.
No club in top-flight history has avoided relegation after losing as many of their opening 16 matches as Bolton. Manager Owen Coyle admits his side's predicament is "absolutely killing" him. Failure to beat Blackburn would likely be a fatal blow - only West Brom have gone on to avoid relegation after propping up the table on Christmas Day.
MATCH FACTS
Head-to-head
Blackburn have only lost one of their last nine league meetings with Bolton, a 2-1 defeat a year ago at the DW Stadium.
Rovers have won three of the last four meetings at Ewood Park, drawing the other.
Blackburn
Blackburn have only won seven league games since Steve Kean took charge a year ago.
They are 11 points worse off after 16 games compared to last season.
Rovers have lost six of their first eight home matches of a top-flight season for the first time.
They have failed to keep a clean sheet in 19 matches since beating Bolton in April - their worst run in the top flight for 80 years.
Bolton
Bolton have lost their last five league games and 13 of their first 16 this season.
They have conceded more goals than any other team in the top flight (38).
The Trotters have lost all 12 league matches in which they conceded the first goal this season.
Mark Davies is likely to make his 100th career league appearance, while Kevin Davies will play his 350th game for Bolton.